Examination of tissue excised for the diagnosis is Histopathology. It remains the final diagnosis in most of the cases and is gold standard method of diagnosis in various disease conditions. When treating physician, excise entire organ or tissue, it is received by the pathology laboratory. The specimens received by the pathology laboratory are then analysed using various techniques.
Principally, there are two types of specimens:
Specimens received by the pathology laboratory require initial tissue preparation, then are treated and analysed using techniques appropriate to the type of tissue and the investigation required. It is used to diagnose, cancerous and non-tumorous conditions.
Histopathology enables professionals to look for changes in cells that explain the actual cause of the patient’s illness. Pathologists are able to reach a diagnosis by examining a small piece of tissue from various organs. Histopathology is vital as it broadens and progresses treatments options.
The tissue that is studied comes from a biopsy or surgical procedure whereby a sample of the suspect tissue is selected and sent to the laboratory. It is then processed and cut into very thin layers (called sections), stained, and examined under microscopes to characterize the details of the cells in the tissue.
Generally, after a patient receives positive melanoma results, his or her doctors will need to proceed with staging the malignancy— which essentially means determining the extent of cancer—and developing a treatment plan based on how far cancer has progressed.